Metabolism is the sum of life-sustaining chemical reactions in cells, including those that turn food into energy and build cellular structures. In recent years, biomedical researchers have intensified their focus on how metabolic processes work in healthy conditions and how those processes go awry in disease. But for Whitehead Institute scientists, this is nothing new. For decades, they’ve been studying the role of metabolism in conditions ranging from obesity and diabetes to cardiac disease and cancer — with profound results.

Please partner with researchers such as David SabatiniHazel Sive, and Jing-Ke Weng as they unravel the metabolic roots of disease.