Type-I diabetes is a complex disease caused by the destruction of beta cells within the pancreas cells through self-reacting T cells within one’s immune system. Whitehead researchers are focused on establishing an in vivo experimental platform that would allow for the study of Type-I diabetes in a humanized animal system. This project combines the researcher’s expertise in cell technology to create a chimeric platform that would allow for the investigation of the disease throughout the animal’s lifetime representing an innovative platform to devise novel therapeutic strategies.

Please partner with researcher Rudolf Jaenisch as he and others make further strides toward understanding and treating Type 1 Diabetes.